Coherent Chameleon Family of LasersCoherent Chameleon DiscoveryCoherent Chameleon UltraCoherent Chameleon VisionCoherent Chameleon Pre-Comp Accessory
Coherent Chameleon Family of Lasers

Chameleon Family

Chameleon lasers feature the widest tuning range and highest power at any wavelength, expanding the frontiers of Multiphoton Excitation (MPE) microscopy and non-linear optical studies.

  • Chameleon Discovery - Chameleon Discovery one-box, wide tuning range, dual output laser for MPE. Now available with Total Power Control: fast power modulation of both outputs.
  • Chameleon Vision and Vision S - One-box laser solution with integrated precompensation.
  • Chameleon Ultra - The flag ship of widely tunable, hands-free, modelocked Ti:Sapphire lasers.
  • Chameleon Compact OPO and MPX - Automated wavelength extension for Chameleon Ti:Sapphire lasers.
  • Chameleon VUE Harmonics - Automated, hands-free Harmonics Generation options for visible and deep UV wavelengths.

See and read more below.

The Ultimate Portfolio of Femtosecond, Tunable Laser Sources

Multiphoton microscopy demands laser technology that is simple to use, yet flexible enough to allow you to explore the widest range of wavelengths and fluorophores. With the release of the new Chameleon Discovery, Coherent now truly offers the most powerful and flexible range of ultrafast technology designed for completely hands-off operation.

Chameleon Discovery is a high power, one-box, wide tuning range, dual output laser for Multiphoton Excitation. Literally two lasers in one, it truly redefines the boundaries of what is possible for deep, in-vivo imaging of all popular probes along with developing red shifted calcium indicators and opsins for optogenetics. The all-new model of the Chameleon Discovery with Total Power Control adds built-in, fast power modulation to both outputs, giving full control of beam parameters into a 2P microscope and streamlining the setup process so users can concentrate on acquiring quality data, rather than optimizing optical delivery systems.

Chameleon Ultra and Vision Series of Ti:Sapphire lasers are market proven performers and workhorses of the MPE community.

Chameleon Ultra delivers optical pulses with GVD characteristics matched to most commercial MPE microscopes whilst delivering high average power and the widest tuning range (680-1080 nm). By incorporating our proprietary Power Pulse system, Chameleon can change color quickly (faster than 40 nm/s) whilst optimizing output power and pulse width automatically.

Chameleon Vision lasers add automated dispersion precompensation to deliver short pulses right to the sample plane, and the Vision-S, short pulse (75 fs) system, delivers higher peak power than any other automated tunable Ti:sapphire laser available.

The Chameleon MPX, is a wavelength extension that is pumped by Chameleon Ultra or Vision lasers and gives access to wavelengths up to 1340 nm. Its unique dual tunablity capability enables powerful multimodal imaging techniques.

Chameleon Compact OPO and Compact OPO VIS extend the wavelength range of the Chameleon Ti:Sapphire laser from 340 nm to 4000 nm, for ultrafast spectroscopy and non-linear optics studies.

Chameleon Family Specifications
Output Power (W)
Tuning Range (nm)
Chameleon Discovery NX
>3.6 W at 800 nm, >3.5 W at 1040 nm
660 to 1320, Fixed 1040, Dual Output
Chameleon Ultra
>2.5 at 800 nm
690 to 1020
Chameleon Ultra I
>2.9 at 800 nm
690 to 1040
Chameleon Ultra II
>3.5 at 800 nm
680 to 1080
Chameleon Vision I
>2.5 at 800 nm
690 to 1040
Chameleon Vision II
>3.0 at 800 nm
680 to 1080
Chameleon Vision S
>2.5 at 800 nm
690 to 1050
Chameleon Compact OPO
> 700 mW
1000 to 1600 (up to 4000nm with idler option) Dual Output
Chameleon MPX
>750 mW
1010 to 1340 Dual Output
Chameleon Compact OPO-Vis
> 700 mW 1100 nm > 1400 mW at 400 nm
340 -1600 nm (up to 4000nm with idler option) 5 outputs

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Coherent has been enlightening lifescience imaging for more than 25 years. Use the link below to learn about the Coherent products that have been making it possible for MPE users to focus on their samples instead of the laser equipment.
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